Projects

 

Running Projects

International Projects

Bilateral projects

  • Mobility SK-PL
    Azobenzenes as potential Alzheimer’s therapeutic agents
    Principal investigator: RNDr. Zuzana Bednarikova, PhD.
    Duration: 01.01.2023 – 31.12.2024
  • SAS-MOST Joint Research Project
    Anti-amyloid activity of zeolite-based composites and analysis with real-time 3d super-resolution imaging
    Principal investigator: RNDr., Ing. Katarína Šipošová, PhD.
    Duration: 01. 01. 2022 – 31. 12. 2024
  • PPP SK-DAAD Project
    Hybrid DNA-functionalized fibrils as nanostructured material for bioanalytical applications
    Principal investigator: RNDr., Ing. Katarina Siposova, PhD.
    Duration: 01. 01. 2022 – 31. 12. 2024

National Projects

Slovak Research and Development Agency (SRDA)  

 

  • Multicomponent ligands as modulators of Azheimer´s disease  pathology-relevant targets
    Principal investigator: Doc. RNDr. Zuzana Gažová, DrSc.
    Duration: 01.07.2023 – 30.06.2027

 

  • Flexible microstructures and micro-robots for biomedical lab-on-chip applications
    Principal investigator: Doc. Ing. Zoltan Tomori, CSc.
    Duration: 01.07.2022 – 30.06.2026

 

  • The development of translationally relevant regenerative and reparative strategies after spinal cord trauma
    Principal investigator: MUDr. Andrey Musatov, DrSc.
    Duration: 01.07.2020 – 30.06.2024

 

Scientific Grant Agency of the Slovak Academy of Sciences and Ministry of Education of Slovak Republic  (VEGA)

  • Ionic liquids and deep eutectic solvents as modulators of protein stability and aggregation
    Principal investigator: RNDr. Diana Fedunova, PhD.
    Duration: 01.01.2022 – 31.12.2025
  • Study and modification of properties of spider protein overexpressed in Escherichia coli
    Principal investigator: RNDr., Ing. Katarína Šipošová, PhD.
    Duration: 01.01.2022 – 31.12.2025
  • Analysis of image sequences by deep learning methods in selected biophysical experiments
    Principal investigator: Doc. RNDr. Zoltan Tomori, CSc.
    Duration: 01.01.2022 – 31.12.2024
  • Elucidation of the initial stages of amyloid aggregation of proteins – from mechanism to therapy
    Principal investigator: Doc. RNDr. Zuzana Gažová, DrSc.
    Duration: 01.01.2021 – 31.12.2024
  • New Insight into the Role of Hydrophobic Interactions in Formation and Stability of Proteins Aggregates. Link to Oxidative Stress
    Principal investigator: MUDr. Andrej Musatov, DrSc.
    Duration: 01.01.2021 – 31.12.2023

SAS Research Grants for PhD Students (DoktoGrant)

  • Study of the effects of molecular hybrids on amyloid aggregation of globular proteins and IDPs
    Principal investigator: RNDr. Barbora Borovská
    Duration: 01.01.2022 – 31.12.2022

Finished Projects

Bilateral projects

  • Slovak Research and Development Agency (SRDA)  Bilateral project between Department of Biophysics Institute of Experimental Physics SAS and Taiwan
    Interactions of nanoparticles with amyloid fibrils: from therapy to nanomaterials
    Principal investigator: Doc. RNDr. Zuzana Gazova, DrSc.
    Duration: 01.01.2022 – 31.12.2023
  • PPP SVK-DAAD project
    Self assembly and functionalization of nanofibrillar DNA-spider silk hybrid materials
    Principal investigator: RNDr., Ing. Katarina Siposova, PhD.
    Duration: 1. 1. 2022 – 31. 12. 2023
  • Bilateral Mobility BAS-SAS Project
    Stability and aggregation of globular proteins in the presence of biocompatible ionic liquids 
    Principal investigator: RNDr. Diana Fedunova, PhD.
    Duration: 01. 01. 2020 – 31. 12. 2022
  • Bilateral Joint Research Project between Institute of Experimental Physics and Vernadskii Institute of General and Inorganic Chemistry of NAS of Ukraine (Ukraine)
    Enhancement of Bioactivity of Cerium Oxide Nanoparticles
    Principal investigator: MUDr. Andrej Musatov, DrSc.
    Duration: 01. 01. 2020 – 31. 12. 2022
  • Bilateral Joint Research Project between Institute of Experimental Physics and Biological Research Centre, Institute of Biophysics, Szeged (Hungary)
    Elastic micro-tools for optical manipulation of biological object
    Principal investigator: Doc. RNDr. Zoltan Tomori, CSc.
    Duration: 01. 01. 2019 – 31. 12. 2021
  • Bilateral Joint Research Project between Institute of Experimental Physics and National Institute of Mental Health (Czech Republic)
    Study of the amyloid aggregation in vitro and in cerebrospinal fluid 
    Principal investigator for Slovak Republic: Doc. RNDr. Zuzana Gažová, CSc..
    Duration: 01. 01. 2015 – 31. 12. 2020
  • Bilateral Joint Research Project between Institute of Experimental Physics and National Institute of Mental Health (Czech Republic)
    Study of the amyloid aggregation in vitro and in cerebrospinal fluid
    Principal investigator: Doc. RNDr. Zuzana Gažová, CSc.
    Duration: 01. 01. 2015 – 31. 12. 2020
  • Bilateral Project between Department of Biophysics Institute of Experimental Physics SAS and Department of Pharmaceutical Science, School of Pharmacy, East China University of Science and Technology, Shanghai, China
    SK-CN-2017-0033 – Discovery and Mechanism of Small Molecule Compounds from Traditional Chinese Medicine for treatment of Alzheimer’s Disease
    Principal investigator for Slovak Republic: Doc. RNDr. Zuzana Gažová, CSc.
    Duration: 01. 01. 2018 – 31. 12. 2019
  • Bilateral Joint Research project between Department of Biophysics Institute of Experimental Physics SAS and National Cheng-Chi University & Academia Sinica
    SK-TW-2017-0012 Study of orientation ordering and self-assembly in biopolymer and liquid crystal
    Principal investigator for Slovak Republic: RNDr., Ing. Katarína Šipošová, PhD.
    Duration: 01. 01. 2018 – 31. 12. 2019
  • Bilateral Project between Department of Biophysics Institute of Experimental Physics SAS and Taiwan
    Effect of small molecules and nanoparticles on amyloid aggregation of poly/peptides
    Principal investigator for Slovak Republic: Doc. RNDr. Zuzana Gažová, CSc.
    Duration: 01. 01. 2016 – 31. 12. 2018
  • Bilateral Project between Department of Biophysics Institute of Experimental Physics SAS and Department of Pharmaceutical Science, School of Pharmacy, East China University of Science and Technology, Shanghai, China
    The multitarget low molecular compounds from traditional Chinese herbs in treatment of Alzheimer´s disease
    Principal investigator for Slovak Republic: Doc. RNDr. Zuzana Gažová, CSc.
    Duration: 01. 01. 2016 – 31. 12. 2017
  • Bilateral Project between Department of Biophysics Institute of Experimental Physics SAS and aInstituto per lo Studio dei Materiali Nanostrutturati, Consiglio Nazionale delle Ricerche, Bologna, Italy
    Amyloid aggregation of proteins in hybrid interfaces 
    Principal investigator for Slovak Republic: Doc. RNDr. Zuzana Gažová, CSc.
    Duration: 01. 01. 2013 – 31. 12. 2017

National Projects

Slovak Research and Development Agency (SRDA)    

  • Interactive methods of image acquisition and processing in microscopy using natural user interface
    Principal investigator: Doc. Ing. Zoltán Tomori, CSc.
    Duration: 01.07.2012 – 31.12.2015
  • Automation of biophysical experiments using light-driven microrobots
    Principal investigator: Doc. Ing. Zoltan Tomori, CSc.
    Duration: 01.07.2016 – 30.06.2020
  • Multi-target inhibitors of poly/peptides associated with Alzheimer´s disease
    Principal investigator: Doc. RNDr. Zuzana Gažová, DrSc.
    Duration: 01.07.2019 – 01.06.2023

VEGA

  • Supramolecular complexes of proteins – conformational transitions, stability and aggregation
    Principal investigator: RNDr. Diana Fedunová, PhD.
    Duration: 01.01.2018 – 31.12.2021
  • Novel statistical and correlation methods in analysis of parametric models of surfaces and their distributions
    Principal investigator: RNDr. Jozef Marek, PhD.
    Duration: 01.01.2019 – 31.12.2021
  • Self-assembly of poly/peptides into amyloid aggregates – mechanism, inhibition and cytotoxicity
    Principal investigator: Doc. RNDr. Zuzana Gažová, CSc.
    Duration: 01.01.2017 – 31.12.2020
  • Functional and structural Insights into the phospholipid-protein interaction during oxidative stress 
    Principal investigator: MUDr. Andrej Musatov, DrSc.
    Duration: 01.01.2017 – 31.12.2020
  • Supramolecular complexes of biomacromolecules
    Principal investigator: RNDr. Eva Valušová, PhD.
    Duration: 01. 01. 2016 – 31. 12. 2019
  • Spintronics on carbon nanoparticles
    Principal investigator: RNDr. Michal Pudlák, PhD.
    Duration: 01. 01. 2016 – 31. 12. 2018
  • Natural User Interface based on RGB-D Image Processing Algorithms and their Application in Biomedicine 
    Principal investigator: Doc. Ing. Zoltan Tomori, CSc.
    Duration: 01. 01. 2016 – 31. 12. 2018
  • Study of the intrinsically disordered protein stability and aggregation
    Principal investigator: RNDr. Diana Fedunová, PhD.
    Duration: 01. 01. 2014 – 31. 12. 2017
  • Development and implementation of algorithms and methods for the study of fiber like objects using image processing and mathematical modeling
    Principal investigator: Ing. Erna Demjén, PhD.
    Duration: 01. 01. 2014 – 31. 12. 2016
  • Functionality and Structural Integrity of Proteins in Bicelles – Implications for Mitochondrial and Amyloidogenic Proteins
    Principal investigator: MUDr. Andrey Musatov, DrSc.
    Duration: 01. 01. 2014 – 31. 12. 2016
  • Inhibitors of protein amyloid aggregation
    Principal investigator: Doc. RNDr. Zuzana Gažová, CSc.
    Duration: 01. 01. 2013 – 31. 12. 2016
  • Supramolecular complexes of proteins
    Principal investigator: Prof. Ing. Marián Antalík, DrSc.
    Duration: 01. 01. 2012 – 31. 12. 2015

SAS Research Grants for PhD Students (DoktoGrant)

  • Study of the effects of molecular hybrids on amyloid aggregation of globular proteins and IDPs
    Principal investigator: RNDr. Barbora Borovská
    Duration: 01.01.2022 – 31.12.2022
  • Study of anti-oxidant and enhanced anti-amyloid activity of cerium nanoparticles for biomedical applications
    Principal investigator: Mgr. Ivana Garčárová
    Duration: 01.01.2021 – 31.12.2021
  • Ionic liquids as amyloid aggregation modulators 
    Principal investigator: RNDr. Vladimír Vaník
    Duration: 01.01.2020 – 31.12.2020