Contacts
Intranet
SK
National
| VEGA – Kalcium fosfátové biocementy s biologicky aktívnou kvapalnou zložkou | |
| – | |
| Program: | VEGA |
| Project leader: | MVDr. Giretová Mária, PhD. |
| Duration: | 1.1.2023 – 31.12.2025 |
| CAMBIOMAT – Chorioalantoická membrána – in vivo model pre štúdium biokompatibility materiálov | |
| Chorioallantoic membrane – in vivo model for study of biocompatibility of materials | |
| Program: | SRDA |
| Project leader: | Ing. Medvecký Ľubomír, DrSc. |
| Duration: | 1.7.2021 – 30.6.2025 |
| Vytváranie vezikúl na báze fosfolipidoiv sd cieľom riadeného uvoľňovania vitamínu K | |
| – | |
| Program: | Intra-constitutional |
| Project leader: | Ing. Štulajterová Radoslava, PhD. |
| Duration: | 1.1.2024 – 31.12.2024 |
| Komponat – Kompozitné biomateriály s komplexnými prírodnými aditívami | |
| Composite biomaterials with complex natural additives | |
| Program: | SRDA |
| Project leader: | Ing. Medvecký Ľubomír, DrSc. |
| Annotation: | The project is focused on the research of modified and new types of composite biocements with complex natural additives, which will self-hardened as well as injectable according to the need for use and will be characterized by high bioactivity and biocompatibility with bone tissue. In principle, the preparation of composite biocement systems is applied in combination with complex natural additives without specific extraction of selected groups of compounds from natural products what preserves the simplicity of preparation, cheap final form of biomaterial as well as the "green principle" of their nature, composition and response. Composite biocements will be used inorthopedics (treatment of bone and osteochondral defects and fractures) as well as in the reconstruction of bone injuries in the facial part or as filling cements in dentistry. |
| Duration: | 1.7.2021 – 30.6.2024 |
| Kompozitné systémy na báze bioelastomérov a bioaktívnych fáz | |
| Composite systems based on bioelastomers and bioactive phases | |
| Program: | VEGA |
| Project leader: | RNDr. Sopčák Tibor, PhD. |
| Annotation: | As the population continues to grow, so does the number of surgeries in various fields of medicine, including reconstructive surgery and regenerative medicine. This implies a need for a research of such biomaterials that will closely mimic the structure of the original tissue. The present project will aim to address the issues related to the currently used bone implants, i.e. low mechanical properties with the simultaneous maintenance of their biological properties. The production of composite systems based on bioelastomers and bioactive phases in the form of bioceramics or cements is expected to take advantage of both components with the outstanding bioactivity, self-setting and handling properties of cements along with excellent elastic properties, mechanical reinforcement and improved biodegradation offered by elastomers. A great emphasis will be given on the production of glycerol carboxylate polyesters and their effective incorporation into the bioactive matrix. |
| Duration: | 1.1.2021 – 31.12.2023 |
| Kompozitné horčíkovo-vápenato fosforečné biocementy s prídavkom koloidného oxidu kremičitého | |
| Composite magnesium-calcium phosphate biocements with addition of colloidal silicon dioxide | |
| Program: | VEGA |
| Project leader: | Ing. Štulajterová Radoslava, PhD. |
| Annotation: | The project is focused on the research and development of composite calcium phosphate biocements containing magnesium and colloidal silica particles, which represents an improvement in particular, in the viscositycharacteristics of cement pastes. The intention is that the addition of colloidal SiO2 will contribute to a fastertransformation of calcium phosphate biocement to calcium deficient hydroxyapatite and change or improving the biocement characteristics, which are important in bone reconstruction. Resulting biocement system should haveenhanced mechanical strength that would be sustained over a longer time period during soaking in body fluids and should positively affect bioresorption with an active influence on specific cell lineages. |
| Duration: | 1.1.2020 – 31.12.2022 |
| VIFKDBB – Výskum inovatívnych foriem liečenia kostných defektov prepojením bioaktívnych biomateriálov s autológnymi rastovými faktormi | |
| Research of innovative forms treatment of bone defects by joining bioactive biomaterials and autologous growth factors | |
| Program: | Vedecko-technické projekty |
| Project leader: | Ing. Medvecký Ľubomír, DrSc. |
| Duration: | 15.12.2018 – 14.12.2021 |
| INJEHYB – Injektovateľné hybridné kompozitné biocementy | |
| Injectable hybrid composite biocements | |
| Program: | SRDA |
| Project leader: | Ing. Medvecký Ľubomír, DrSc. |
| Annotation: | Project is focused on synthesis, preparation and characterization of modified and novel types of injectable hybridbiocements with high bioactivity, structure and chemical biocompatibility with required properties for medicalapplications. Above biomaterials will have widely utilization in orthopeadics (therapy of bone defects andfractures, stabilization of endoprosthesis etc.), for reconstruction of bone injuries in maxillofacial region and like bioactive adhezive cements in dentistry. |
| Duration: | 1.8.2018 – 30.6.2021 |
| Biomimeticky vytvrdzované hydrogél/kalcium fosfátové cementy | |
| Biomimetically hardened hydrogel/calcium phosphate cements | |
| Program: | VEGA |
| Project leader: | Ing. Medvecký Ľubomír, DrSc. |
| Annotation: | The project is focused on research and development of hydrogel / calcium phosphate cements with optimized content of calcium and phosphate ions concentrated in hydrogels. This arrangement allows biomimetic precipitation of calcium phosphate nanoparticleswith specific ordering, which will affect the strength of the interface, microstructure and properties of cement composites. The objective of the project will be research and development of new method for creating of larger pores using resorbable macroporous particles added to the cement paste and analysis relation of characterstics of cement particles on the final cement properties. Final systems will mimic the composition of bone tissue and imitate the ossification processes of bone tissue formation via hydrogel component. |
| Duration: | 1.1.2017 – 31.12.2019 |
| Hybridné kompozitné systémy s bioskelnou zložkou | |
| Hybrid composite systems with bioglass component | |
| Program: | VEGA |
| Project leader: | Ing. Medvecký Ľubomír, DrSc. |
| Annotation: | Project is focused on research and development of hybride composite systems with bioglass component applicable in reconstruction and regenerative medicine. The aim of the project is a more detailed analysis of relationships between interaction of various types of polymer phase, synthesized during preparation ofcomposites, with surface of bioglass particles and its influence on microstructure, mechanical properties and biodegradation of composites. An important part of the project is study of nanohybride composites with homogeneous silico-organic matrix formed by sol-gel synthesis. |
| Duration: | 1.1.2014 – 31.12.2016 |