Nanoceria and Carbon Enterosorbents Composites for Acute Radiation Sickness Therapy

The research group from the Institute of Experimental Physics Slovak Academy of Sciences in Kosice has recently obtained funding for a new project in the framework of the NATO – Science for Peace and Security call for proposals. The project “Novel Composites based on Cerium Oxide Nanoparticles and Carbon Enterosorbents for Acute Radiation Sickness Therapy” (project G5683) is coordinated by Prof. Svitlana Lyubchyk, leading researcher of the Associação para a Inovação e Desenvolvimento da FCT, Universidade Nova de Lisboa, Portugal. The consortium also includes the researchers from the Department of Biophysics and Department of Magnetism of Institute of Experimental Physics in Kosice (PI Dr. Andrey Musatov); the Vernadskii Institute of General & Inorganic Chemistry, NAS of Ukraine; the Kavetskii Institute of Experimental Pathology, Oncology & Radiology, NAS of Ukraine, and Departamento de Quimica Inorganica, Universidad de Alicante in Spain. In the next 3 years members of the research groups will design and test the novel nanocomposites for the treatment of acute radiation sickness based on the combined use of uncoated nanocrystalline cerium dioxide and the newest highly active oral dispersible carbon enterosorbents. The practical result of the study will be an experimental implementation of a completely new approach to mass therapy of acute radiation sickness, compatible with classical cytokine therapy. It is expected that the research will lead to a new medicinal product ready to be tested in a preclinical trials.

Text: K. Šipošová