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| Citlivosť kvapalných kryštálov s nanočasticami na vonkajšie magnetické pole | |
| Sensitivity of liquid crystals containing nanoparticles to external magnetic field | |
| Program: | VEGA |
| Project leader: | doc. RNDr. Kopčanský Peter, CSc. |
| Annotation: | The proposed project will devoted to the study of composite systems of liquid crystal with nanoparticles mainly magnetic particles with the aim to change their sensitivity to external magnetic field. The object of such study will be new kind of liquid crystals with bent-core molecules as well as traditional calamitic liquid crystals with rod-like molecules. Also the influence of magnetic particles on the structural phase transition from isotropic to nematic phase in external magnetic field will be investigated. We suppose this structural transition will be induced by external magnetic field. Moreover, the response of the above mentioned composite systems to low magnetic field (up to 0.1T) will be investigated, which is important for the construction of various magneto-optical devices as for example maping of magnetic fields. |
| Duration: | 1.1.2013 – 31.12.2016 |
| Výpočtové prístupy štúdia štruktúry, zbaľovania a interakcií biopolymérov | |
| Computational approaches to study structure, folding and interactions of biopolymers | |
| Program: | Podpora MVTS z prostriedkov SAV |
| Project leader: | RNDr. Kožár Tibor, CSc. |
| Annotation: | The PI of this research proposal (Dr. Chin-Kun Hu), CoPI of this proposal(Dr. Ming-Chya Wu), and their collaborators (including Dr. Shura Hayryan, and collaborators from Slovakia, Yerevan, Berlin, etc) have developed protein and computation packages SMMP (simple molecular mechanics for proteins), ARVO (to calculate volume and surface of macromolecules, including proteins, DNA, RNA, etc), and CAVE (to detect cavities of macromolecules and calculate surface area and volumes of cavities). The PI and collaborators also developed efficient combination of Wang-Landau Monte Carlo methods and transition matrix Monte-Carlo method for simulating proteins. They have also calculated three-dimensional (3D) structures of a large numbers of microRNA and will establish a website for such 3D structures.. The PI of the collaborative group in Slovakia, Dr. Tibor Kozar (Department of Biophysics, Institute of Experimental Physics, Slovak Academy of Sciences) is an expert on modeling of glycans and glycoproteins. In this proposal, we will continue to improve SMMP, ARVO, CAVE, microRNA molecular dynamics calculations, and will collobrate with Dr. Tibor Kozar’s group to study glycan and glycoproteins and amyloid aggregates. In addition, significant effort will be devoted to interaction studies of ligands with biomacromolecules nucleic acids and proteins with both, small ligands (potential drugs) as well as nanoparticles in order to target amyloid aggregation being this important for diseases (e.g. Alzheimer\’s disease). |
| Duration: | 1.1.2011 – 31.12.2013 |
| NANOFLUID – Centrum excelentnosti SAV – Nanokvapaliny | |
| Centre excelence of SAS – Nanofluids | |
| Program: | Centrá excelentnosti SAV |
| Project leader: | doc. RNDr. Kopčanský Peter, CSc. |
| Annotation: | Centre of NANOFLUIDS is oriented to development of technology of nanoparticles, as are magnetic nanoparticles, coloid gold, nanotubes and their complex characterisation from with aspect to their magnetic and morphologic properties. The prepared nanoparticles will be funcionalised for applications in biomedicine, biotechnology and electrotechnical industry. In the case of biomedical applications the interaction of nanoparticles with biomacromolecules will be investigated, mostly with aspect of the nanohazard, drug targeting delivery, hyperthermia and treatment many human diseases as e.g. Alzheimer\’s diseases, etc. For technical applications the centre will investigate opportunity of application in LCD’s, sensors of magnetic field, as an insulated and cooling medium in high power transformers and converters, exploation multilayered nanotubes and fullerenes as electrodes in device that could converts sun energy into electricity. |
| Duration: | 1.2.2009 – 31.1.2013 |
| Štúdium anomálneho škálovania v stochastických a turbulentných systémoch s narušenými symetriami | |
| Study of anomalous scaling in stochastic and turbulent systems with symmetry breaking | |
| Program: | VEGA |
| Project leader: | prof. Dr.h.c. RNDr. Hnatič Michal, DrSc. |
| Annotation: | At present stochastic systems attract intensive interest of scientists. This interest is based on the fact that stochasticity belongs to the basic attributes of macroscopic physical, chemical, biological and, moreover, social-economical systems. Advection of admixtures in random environment (pollutants in the atmosphere of theEarth), crossing of cosmic particles through interstellar space, developed (magneto)hydrodynamic turbulenceare typical examples of stochastic systems.It is just the study of the aforementioned physical systems that will form the core of the project.Anomalous scaling is a crucial and universal feature of stochastic systems. Calculation of representativeparameters of the systems like effective viscosity, Prandtl number, Kolmogorov constant etc. forms an important part of scientific interest.Calculation of anomalous exponents and parameters of the systems with symmetry violation will be the basic objective of the project. |
| Duration: | 1.1.2009 – 31.12.2012 |
| Kooperatívne javy a fázové prechody v nanosystémoch s perspektívou využitia v nano- a biotechnológiách | |
| Centre of excelence: Cooperative phenomena and phase transitions in nanosystems with perspective applications in nano- and biotechnology | |
| Program: | EU Structural Funds Research & Development |
| Project leader: | doc. RNDr. Kopčanský Peter, CSc. |
| Duration: | 24.4.2009 – 31.3.2011 |
| Štúdium korelačných funkcií náhodných polí v kritickej a stochastickej dynamike | |
| Study of correlation functions of random fields in critical and stochastic dynamics | |
| Program: | VEGA |
| Project leader: | prof. Dr.h.c. RNDr. Hnatič Michal, DrSc. |
| Duration: | 1.1.2006 – 31.12.2008 |