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| AMAZON – Dynamické štúdium amyloidnej agregácie proteínov pomocou magnetických zeolitových nanočastíc | |
| Dynamical study of formation/destruction of protein amyloid aggregatess targeted by magnetic zeolite nanocomposites | |
| Program: | JRP |
| Project leader: | doc. RNDr. Kopčanský Peter, CSc. |
| Annotation: | Abnormal protein aggregation and accumulation of formed fibrils are characteristic features for a range of, if not all, neurodegenerative disorders such as Alzheimer’s, Huntington’s, Parkinson’s, as well as non-neuropathic amyloidosis. Nanoparticles (NPs), attributed to its particularities in sizes, chemical composition and surface properties, have already been found effective in influencing amyloid fibrils. Our preliminary results acquired on amyloid fibrils incubated with in-laboratory synthesized Fe3O4 nanoparticles (MNPs) indicated reductive potential of MNPs on formation of amyloid fibrils, and also suggested facilitation of inhibiting preformation and eradication of amyloid fibrils may be plausible when the fibrils are exposed to external radiation in presence of MNPs. Also, with our previously reported photoluminescence properties of natural zeolite (CZ) which is a promising material for biomedicine and pharmaceutics due to its non-toxicity, thermal stability, expanded surface area, and exceptional ability to adsorb various atoms, organic molecules and nanoparticles into micro- and mesopores, we plan to apply the MNPs with CZ, developing multiphoton excitation microscopy (MPEM), and other appropriate instruments to establish the dynamical investigation of amyloid fibril formation and remodeling in real time. Prior to in vivo experiment, cytotoxicity in different type of cells and animal models such as zebrafish and mice will be evaluated. |
| Duration: | 1.1.2018 – 31.12.2020 |
| BIOSAP – Nanoštrukturované bio-hybridné materiály generované samousporiadajúcimi procesmi | |
| Design of nanostructured bio-hybrid materials through self-assembly process | |
| Program: | Bilateral – other |
| Project leader: | RNDr. Tomašovičová Natália, CSc. |
| Annotation: | The aim of the present project proposal is to significantly contribute to the better understanding of the complex interaction between magnetic nanoparticles and host matrix based on the lyotropic liquid crystal. One of the key tasks of the project herein is to prepare bio-inorganic hybrids based on liquid crystals formed by lysozyme fibrils alongside doping of magnetic nanoparticles, to study the interaction between magnetic nanoparticles and lysozyme amyloid fibrils as well as their consequential structure. The project proposal primarily targets experimental research on a phenomenon observed in biological anisotropic colloidal suspensions, which have been extensively studied for its consequential relation with many human neurodegenerative disorders such as Alzheimers disease, Hungtingtons disease, and etc. Self-assembly of colloidal nanomaterials makes it possible to obtain structures with high level of ordering and permit construction of patterns to be used in optoelectronics, photonics and biosensing. However, the exact principle of mechanisms and the nature of the phenomenon are still unknown, and represent unexplored areas of research. Various experimental techniques already available at the collaborating institutions as detailed below will be employed to attain the main objective of the project as well as the related objectives itemized in the proposal. |
| Duration: | 1.1.2018 – 31.12.2019 |
| Teoretické a experimentálne štúdium orientačných, magneto-optických a dielektrických vlastností kompozitov kvapalných kryštálov dopovaných magneticckými časticami. | |
| Theoretical and experimental studies of orientational, magneto-optical and dielectric properties of composite liquid crystals filled with magnetic particles. | |
| Program: | Inter-academic agreement |
| Project leader: | RNDr. Tomašovičová Natália, CSc. |
| Annotation: | At the last decades, one of the important areas of modern soft matter physics is theoretical and experimental study of liquid crystals (LC) which are very attractive for use in various commercial exploitations. The great interest of researchers to this area of science is explained, first of all, by fast development of electronic technique and communication equipments which require reliable, convenient and compact devices for processing and displaying information – indicators, displays, screens, etc. The successful use of LC materials in such devices considerably expanded a circle of technical applications of liquid crystals: now they are applied also in modern industrial machineries, in different transport vehicles and systems, medicine, household appliances, etc. Additionally, the search for new materials with exotic properties and for new technologies continues, in order to comply with the needs of these, and other novel applications. |
| Duration: | 1.1.2017 – 31.12.2019 |
| MAPACON – Magnetické vlastnosti anizotrópnych kompozitnych systémov | |
| Magnetic properties of anisotropic composite nanosystems | |
| Program: | Bilateral – other |
| Project leader: | RNDr. Tomašovičová Natália, CSc. |
| Annotation: | The aim of the present project proposal will significantly contribute to the better understanding ofthe complex interaction between the liquid crystalline matrix and the nanoparticles inferronematics (nematics liquid crystals doped with magnetic nanoparticles). The investigationand understanding of the interaction will help to prepare composite systems with highersensitivity to external magnetic field. Our preliminary (unpublished) results, devoted to studyingof magnetic properties of ferronematics, indicate a clear signature of the phase transitions (boththe isotropic to nematic and the nematic to crystal phase) in the magnetic properties of thesecomposite nanosystems: the ac susceptibility changes substantially at temperatures which canbe associated with the phase transition temperatures. The effect has neither been observed inundoped nematic liquid crystals, nor in pure nanoparticle systems. Therefore, it is reasonable tosuppose that the effect originates from the interactions between the nanoparticles and the liquidcrystal host. However, the exact cause, and the nature of the phenomenon is still unknown andrepresents an unexplored area of research. |
| Duration: | 1.1.2015 – 31.12.2016 |
| MACOSYS – Magneticky aktívne anizotrópne kompozitne systémy | |
| Magnetically active anisotropic composite systems | |
| Program: | ERANET |
| Project leader: | doc. RNDr. Kopčanský Peter, CSc. |
| Annotation: | The proposal relates to basic research of anisotropic soft materials sensitive to magnetic fields. The targeted substances are composite materials, so called ferronematics (nematic liquid crystals (LCs) doped with spherical, rod-like, chain-like magnetite nanoparticles, or with carbon nanotubes functionalized with magnetite nanoparticles), and the cross-linked liquid crystalline polymers (elastomers) doped with nanoparticles. The key objectives are: (i) to measure the optical and dielectric responses of these materials to low magnetic fields; (ii) to explore which conditions influence these responses (e.g., bias magnetic field, pretilt, anchoring between the liquid crystal and nanoparticles); (iii) to contribute to the better understanding of the major problem in ferronematics (FNs): the aggregation process; (iv) to enhance the magnetic field induced phase transition temperature shift in a novel type of FNs; (v) to produce mesogenic cross-linked composites sensitive to magnetic fields. |
| Duration: | 1.9.2013 – 31.8.2016 |
| MAPACON – Magnetické vlastnosti anizotrópnych kompozitnych systémov | |
| Magnetic properties of anisotropic composite nanosystems | |
| Program: | Bilateral – other |
| Project leader: | RNDr. Tomašovičová Natália, CSc. |
| Annotation: | The aim of the present project proposal will significantly contribute to the better understanding ofthe complex interaction between the liquid crystalline matrix and the nanoparticles inferronematics (nematics liquid crystals doped with magnetic nanoparticles). The investigationand understanding of the interaction will help to prepare composite systems with highersensitivity to external magnetic field. Our preliminary (unpublished) results, devoted to studyingof magnetic properties of ferronematics, indicate a clear signature of the phase transitions (boththe isotropic to nematic and the nematic to crystal phase) in the magnetic properties of thesecomposite nanosystems: the ac susceptibility changes substantially at temperatures which canbe associated with the phase transition temperatures. The effect has neither been observed inundoped nematic liquid crystals, nor in pure nanoparticle systems. Therefore, it is reasonable tosuppose that the effect originates from the interactions between the nanoparticles and the liquidcrystal host. However, the exact cause, and the nature of the phenomenon is still unknown andrepresents an unexplored area of research. |
| Duration: | 1.1.2015 – 31.12.2015 |
| – | |
| Nanoparticles in anisotropic soft matter | |
| Program: | Inter-academic agreement |
| Project leader: | RNDr. Tomašovičová Natália, CSc. |
| Annotation: | Liquid crystals and liquid crystalline polymers are anisotropic fluids, and as such they are in general responsive to external stimuli. However, because of the small value of the anisotropy of the diamagnetic susceptibility (~10-7), they require rather high magnetic fields for a measurable response. In an effort to enhance the magnetic susceptibility, the idea of doping with magnetic particles was theoretically introduced more than fourty years ago. The experimental confirmations of the idea followed shortly, however, the results have been mainly found unreproducible indicating that the colloids were not stable. The research on this topic (especially on ferronematics) has been intensified in the last decade, and a number of experimental evidences has been given for obtaining stable composite materials when the concentration of the magnetic nanoparticles is kept low enough. In a recent paper [Soft Matter 7, 4742 (2011)] an experimental confirmation has been given for a measurable optical response of a ferronematic already at magnetic field of about 0.01T. The observation of the response at such a low field is very important for construction of various magneto-optical devices. We expect that our proposed research will contribute to a better understanding of the physics of the anisotropic colloidal systems, which represents the first step in designing materials with improved magnetic properties, and helps to establish the knowledge base to utilize related future technologies. |
| Duration: | 1.1.2013 – 31.12.2015 |
| Anizotrópne magnetické kvapaliny | |
| Anisotropic magnetic fluids | |
| Program: | Inter-academic agreement |
| Project leader: | RNDr. Tomašovičová Natália, CSc. |
| Duration: | 1.1.2010 – 31.12.2012 |
| MAGIC – Magneticky aktívne anizotrópne kvapaliny | |
| Magneticlally active anisotropic fluids | |
| Program: | Bilateral – other |
| Project leader: | RNDr. Tomašovičová Natália, CSc. |
| Duration: | 1.2.2009 – 31.12.2010 |
| Štruktúrne fázové prechody v tekutých kryštáloch dopovaných magnetickými nanočasticami | |
| The structural phase transition in liquid crystals doped by magnetic nanoparticles | |
| Program: | Inter-academic agreement |
| Project leader: | RNDr. Tomašovičová Natália, CSc. |
| Annotation: | no description |
| Duration: | 1.1.2007 – 31.12.2009 |
| Štruiktúrne fázové prechody v kvapalných kryštáloch dopovaných magnetickými nanočasticami | |
| Structural phase transitions in liquid crystals doped with magnetic nanoparticles | |
| Program: | Bilateral – other |
| Project leader: | RNDr. Tomašovičová Natália, CSc. |
| Duration: | 1.3.2007 – 31.12.2008 |
National
| NANOFLIT – Nano-funkcionalizácia kvapalín pre olejové transformátory | |
| Nano-functionalization of liquids for liquid-immersed transformers | |
| Program: | SRDA |
| Project leader: | RNDr. Rajňák Michal, PhD. |
| Annotation: | The current increase in electricity consumption and the greening of its distribution, together with the increase in the price of materials for the production of distribution transformers, represent a challenge for applied research in electric power engineering. The intention of the presented project is to respond to this challenge by functionalizing the current liquids used in electrical transformers in order to increase their cooling efficiency while maintaining or improving their dielectric and insulating properties. For this project, the liquids used in the distribution transformers of the manufacturer interested in this research will be selected. These are commercial liquids primarily based on liquefied natural gas, synthetic and natural esters. Based on current state of the art, the liquids will be functionalized by means of nanotechnologies and nanomaterials, which can significantly improve thermal conductivity, natural and thermomagnetic convection, and thus make the overall heat transport in the liquids more efficient. The functionalizing nanoadditives will be mainly made from carbon (fullerene, nanodiamond) and iron oxides or other ferromagnetic elements. The functionalized liquids will undergo laboratory measurements of physico-chemical, electrical, magnetic and thermal properties. Based on the analyzes of laboratory experiments and numerical simulations, nanofluids with the greatest potential for improving the thermal and insulating properties of the transformer will be selected. The selected nanofluids will be tested by the industrial partner (the customer of the research results) and applied in the selected distribution transformer. The transformer will be subjected to electrical and temperature rise tests. One can expect that the nanofunctionalization of the liquids will result in a lower operating temperature of the transformer, which can lead to an extension of the transformer service life and to the production of smaller transformers. |
| Duration: | 1.7.2023 – 30.6.2027 |
| Procesy samousporiadania v mäkkých hybridných zmesiach kvapalných kryštálov a nanočastíc | |
| Self-organization processes in soft hybrid mixtures of liquid crystals and nanoparticles | |
| Program: | VEGA |
| Project leader: | RNDr. Tomašovičová Natália, CSc. |
| Annotation: | The proposal aims to approach the research of liquid crystals doped with nanoparticles of different kind from anovel perspective of the self-organization that has an indisputable importance covering all fields of naturalsciences, and has also a deep impact in social sciences. In such composite systems a subtle interplay amongthe nanoparticles, the self-assembling matrix and the topological defects commands the self-organizationprocess. We will focus on the electric/magnetic field induced self-organization in such systems experimentally on different length scales by investigating the processes in different phases, isotropic, nematic, cholesteric with the anticipation that our results can be exploited in applications such as guided material transport, magnetic/electric switches/sensors, chemical/biosensors, in microfluidic/lab-on-a-chip devices, etc. We are convinced that systematic studies in this topic may change fundamentally current knowledge. |
| Duration: | 1.1.2021 – 31.12.2024 |
| NANOELEN – Nanokvapaliny v elektrotechnike | |
| Nanofluids in Electrical Engineering | |
| Program: | SRDA |
| Project leader: | RNDr. Rajňák Michal, PhD. |
| Annotation: | The submitted project is oriented on research into nanofluids based on alternative cooling and insulating liquidmedia such as oils based on liquefied natural gas, natural esters and new types of transformer oils. We willprepare novel nanofluids based on these oils by dispersing magnetic nanoparticles, fullerenes, graphenenanoplatelets or carbon nanotubes. The purpose of the nanofluids preparation is to enhance the coolingeffectiveness of the liquid media. The nanofluids will be investigated from dielectric, insulating, magnetic andheat transfer properties point of view. Finally, their cooling effectiveness will be tested in loaded powertransformers. Therefore, the aim of this project is the development of advanced liquid media for cooling andinsulating in electrical engineering, the application of which will have a potential impact on electric power saving,electrical equipment service life and protection of the environment. |
| Duration: | 1.7.2019 – 30.6.2023 |
| Slzná tekutina a sliny v preventívnej, prediktívnej a personalizovanej medicíne | |
| Tear fluid and saliva in preventive, predictive and personalized medicine | |
| Program: | VEGA |
| Project leader: | RNDr. Tomašovičová Natália, CSc. |
| Annotation: | Tear fluid and saliva are non-traditional biological collected material. Collection is non-invasive, which is anadvantage compared to blood collection as a standard biological material. It is not colored, contains water andelectrolytes, proteins, lipids, hormones and others. Characterization of its composition in various inflammatorydiseases with a focus on amyloid formation by using several methods represents an approach of preventive,predictive and personalized medicine. Body fluid content in patients with pathological conditions variessignificantly compared to healthy subjects. There are still unexplained interindividual changes in non-traditionalbody fluids in clinical-diagnostic practice, but these differences may allow personal diagnosis and application oftailor-made treatments. |
| Duration: | 1.1.2020 – 31.12.2022 |
| EXSES – Exotické kvantové stavy nízkorozmerných spinových a elektrónových systémov | |
| Exotic quantum states of low-dimensional spin and electron systems | |
| Program: | SRDA |
| Project leader: | RNDr. Vargová Hana, PhD. |
| Annotation: | The project is devoted to theoretical study of low-dimensional quantum spin and electron systems, which will beexamined by the combination of advanced analytical and numerical methods including among other mattersexact mapping transformations, transfer-matrix method, strong-coupling approach, classical and quantum MonteCarlo simulations, exact diagonalization and density-matrix renormalization group method. The obtainedtheoretical outcomes will contribute to a deeper understanding of exotic quantum states of spin and electronsystems such as being for instance different kinds of quantum spin liquids as well as quantum states with asubtle long-range order of topological character or with a character of valence-bond solid. The project willsignificantly contribute to a clarification of unconventional magnetic behavior of selected low-dimensionalmagnetic materials and thus, it will have significant impact on a current state-of-the-art in the field of condensedmatter physics and material science. On the other hand, a detailed investigation of quantum entanglement willestablish borders of applicability of the studied spin and electron systems for the sake of quantum computationand quantum information processing. Another important outcome of the project is to clarify nontrivial symmetriesin tensor states of the strongly correlated spin and electron systems affected by either position dependentinteractions or changes in lattice geometries, which induce phase transitions of many types. |
| Duration: | 1.7.2017 – 30.6.2021 |
| Makroskopicky anizotrópne kompozity na báze kvapalnych kryštálov a magnetických nanočastíc | |
| Macroscopic anisotropic composites based on liquid crystals and magnetic nanoparticles | |
| Program: | VEGA |
| Project leader: | RNDr. Tomašovičová Natália, CSc. |
| Annotation: | The proposal targets basic research on composite materials consisting of liquid crystals and various magnetic nanoparticles. Combination of the anisotropic properties of liquid crystals with the magnetic properties of the nanoparticles results in composites with unique magnetic and optical properties that the component materials themselves do not possess. The proposed studies concentrate on the increase of the sensitivity of our composite soft matter materials (liquid state) to magnetic fields and prepare new materials having unique dielectric, magnetic and optical properties. The main goal of the proposal is to influence the sensitivity of these anisotropicsystems to external magnetic field by adding suitable magnetic nanoparticles and by this way make a step forward towards potential applications in various magneto-optical or dielectric devices as for example sensors of low magnetic fields or light shutter. |
| Duration: | 1.1.2017 – 31.12.2020 |
| MVISION – Nanočastice v anizotrópnych systémoch | |
| Nanoparticles in anisotropic systems | |
| Program: | SRDA |
| Project leader: | doc. RNDr. Kopčanský Peter, CSc. |
| Annotation: | The proposal is devoted to study complex anisotropic systems based on thermotropic as well as lyotropic(biological) liquid crystals. Liquid crystals represents the uniq state of matter, which is liquid but posses theanisotropic properties. The structuralization phenomena in such systems play key role in fundamental as well asin applied research. The main aim is to s influence the sensitivity of these anisotropic systems to externalmagnetic field, what will be done by adding suitable magnetic nanoparticles and open the way for theirapplications in magneto-optical devices. |
| Duration: | 1.7.2016 – 31.12.2020 |
| Citlivosť kvapalných kryštálov s nanočasticami na vonkajšie magnetické pole | |
| Sensitivity of liquid crystals containing nanoparticles to external magnetic field | |
| Program: | VEGA |
| Project leader: | doc. RNDr. Kopčanský Peter, CSc. |
| Annotation: | The proposed project will devoted to the study of composite systems of liquid crystal with nanoparticles mainly magnetic particles with the aim to change their sensitivity to external magnetic field. The object of such study will be new kind of liquid crystals with bent-core molecules as well as traditional calamitic liquid crystals with rod-like molecules. Also the influence of magnetic particles on the structural phase transition from isotropic to nematic phase in external magnetic field will be investigated. We suppose this structural transition will be induced by external magnetic field. Moreover, the response of the above mentioned composite systems to low magnetic field (up to 0.1T) will be investigated, which is important for the construction of various magneto-optical devices as for example maping of magnetic fields. |
| Duration: | 1.1.2013 – 31.12.2016 |
| Aplikácia magnetických kvapalín v elektrotechnike | |
| Application of magnetic fluids in electrical engineering | |
| Program: | VEGA |
| Project leader: | RNDr. Timko Milan, CSc. |
| Duration: | 1.1.2012 – 31.12.2015 |
| METAMYLC – Štrukturalizačné javy v systémoch s nanočasticami | |
| Structuralization phenomena in systems with nanoparticles | |
| Program: | SRDA |
| Project leader: | doc. RNDr. Kopčanský Peter, CSc. |
| Annotation: | The structuralization phenomena plays key role in fundamental as well as in applied research. The proposed project is devoted to the study of the influence of nanoparticles on the structuralization phenomena in various systems as well as on the structuralization of the nanoparticles alone. Some special kinds of nanoparticles will be prepared, which will be used for study these effects. The main aim is to study the influence of the nanoparticles on the structuralization phenomena in two different kind of systems as liquid crystalline mater and amyloid structures. In the first system the magnetic particles can increase the sensitivity of liquid crystals on an external magnetic field. In the amyloid structures the nanoparticles can significantly influence the amyloid aggregation of proteins, which is responsible for amyloid diseases as Alzheimher, Parkinson and Dibetes II The prepared nanoparticles will also be used to build their 3D structures (metamaterials), i.e. to create systems with unusual physical properties as for example negative reflection. |
| Duration: | 1.5.2011 – 31.10.2014 |
| NMTE – Nové materiály a technológie pre energetiku | |
| New materials and technologies for energetics | |
| Program: | EU Structural Funds Research & Development |
| Project leader: | Ing. Diko Pavel, DrSc., akademik US Slovenska |
| Annotation: | Aims o the project are:1. Technology of nanostructured bulk superconductors for energy storage2. Biological battery based on renewable biological products3. New trafo-steel modified by nanoparticles 4. Cooling and insulating medium based on magnetic fluid for high power transformers |
| Project webpage: | nmte.saske.sk |
| Duration: | 1.5.2010 – 30.4.2013 |
| Dobudovanie centra pre kooperatívne javy a fázové prechody v nanosystémoch s pespektívou využitia v nano- a biotechnológiách | |
| – | |
| Program: | EU Structural Funds Research & Development |
| Project leader: | doc. RNDr. Kopčanský Peter, CSc. |
| Duration: | 1.4.2010 – 31.3.2013 |
| NANOFLUID – Centrum excelentnosti SAV – Nanokvapaliny | |
| Centre excelence of SAS – Nanofluids | |
| Program: | Centrá excelentnosti SAV |
| Project leader: | doc. RNDr. Kopčanský Peter, CSc. |
| Annotation: | Centre of NANOFLUIDS is oriented to development of technology of nanoparticles, as are magnetic nanoparticles, coloid gold, nanotubes and their complex characterisation from with aspect to their magnetic and morphologic properties. The prepared nanoparticles will be funcionalised for applications in biomedicine, biotechnology and electrotechnical industry. In the case of biomedical applications the interaction of nanoparticles with biomacromolecules will be investigated, mostly with aspect of the nanohazard, drug targeting delivery, hyperthermia and treatment many human diseases as e.g. Alzheimer\’s diseases, etc. For technical applications the centre will investigate opportunity of application in LCD’s, sensors of magnetic field, as an insulated and cooling medium in high power transformers and converters, exploation multilayered nanotubes and fullerenes as electrodes in device that could converts sun energy into electricity. |
| Duration: | 1.2.2009 – 31.1.2013 |
| Štúdium korelačných efektov v silne interagujúcich sústavách fermiónov | |
| – | |
| Program: | VEGA |
| Project leader: | RNDr. Farkašovský Pavol, DrSc. |
| Duration: | 1.1.2010 – 31.12.2012 |
| Vplyv rôznych nanočastíc na štruktúrne prechody vo feronematikách a na dielektricke vlastnosti magnetických kvapalín | |
| Influence of different nanoparticles on the structural transitions in ferronematics and dielectric properties of magnetic fluids | |
| Program: | VEGA |
| Project leader: | doc. RNDr. Kopčanský Peter, CSc. |
| Annotation: | The proposed project will be devoted to the study of some processes in composite systems containing nanoparticles, namely in magnetic fluids and liquid crystals. The first part of the project will be devoted to liquid crystals doped with magnetic nanoparticles of various shape (spherical, rod-like, chain-like) and different kind of nanoparticles (magnetite, CoZnFeO, as well as new attractive gold and silver particles) with aim to influence their dielectric and optical properties in external magnetic and electric fields. The second part of the project will be deal with the investigation of the dielectric properties, partialdischarges and the both DC and AC dielectric breakdown of novel transformer oil based magnetic fluids with same kind of particles as above mentioned, regarding to the possibility of their application in power transformers. |
| Duration: | 1.1.2009 – 31.12.2012 |
| Vývoj tecnologických postupov magnetických kvapalín pre biomedecínske účely | |
| – | |
| Program: | EU Structural Funds Research & Development |
| Project leader: | doc. RNDr. Kopčanský Peter, CSc. |
| Duration: | 1.1.2010 – 30.6.2012 |
| Centrum excelentnosti výkonových elektronických systémov a materiálov pre ich komponenty | |
| Center of excellence for power electronics and their material components | |
| Program: | EU Structural Funds Research & Development |
| Project leader: | RNDr. Timko Milan, CSc. |
| Duration: | 25.5.2009 – 24.5.2011 |
| Kooperatívne javy a fázové prechody v nanosystémoch s perspektívou využitia v nano- a biotechnológiách | |
| Centre of excelence: Cooperative phenomena and phase transitions in nanosystems with perspective applications in nano- and biotechnology | |
| Program: | EU Structural Funds Research & Development |
| Project leader: | doc. RNDr. Kopčanský Peter, CSc. |
| Duration: | 24.4.2009 – 31.3.2011 |
| Štúdium nábojového a magnetického usporiadania v korelovaných sústavách elektrónov | |
| The study of charge and magnetic ordering in correlated electron systems | |
| Program: | VEGA |
| Project leader: | RNDr. Farkašovský Pavol, DrSc. |
| Annotation: | We will study a formation of charge and magnetic ordering in correlated electron systems consisting of two interacting subsystems: the itinerant d-electron subsystem and the localized subsystem of f-electrons or spins. The generating model for a description of such systems will be the spin-one-half Falicov-Kimball model generalized by the spin dependent interaction between d and f electrons (spins) and the Hubbard interaction between the itinerant d-electrons. The main goal is to contribute to understanding the formation of inhomogeneous charge and magnetic ordering, observed experimentally, for example, in the normal phase of high-temperature supreconductors (but also in many others rare-earth and transition metal compounds, e.g. NaxCoO2) as well as to contribute to the theory of itinerant magnetism, electronic ferroelectricity and the theory of metal-insulator transitions that are tightly bound with particular charge and magnetic ordering. |
| Duration: | 1.1.2007 – 31.12.2009 |
| SIPS – Vedecký inkubátor pre žiakov a študentov | |
| Scientific Incubator for Pupils and Students | |
| Program: | SRDA |
| Project leader: | RNDr. Zentková Mária, CSc. |
| Annotation: | The scientific incubator for pupils and students is an attempt to influence the public opinion on the role of chemistry and physics in contemporary society. Its target group varies from kindergarten children, pupils and students to their teachers and their teachers programs. |
| Duration: | 1.10.2006 – 31.12.2009 |
| Cielený transport protinádorových liečiv prostredníctvom magneticky značených nanosfér | |
| Targeted transport of anticancer drugs in magnetically labelled nanoparticles | |
| Program: | SRDA |
| Project leader: | Ing. Koneracká Martina, CSc. |
| Annotation: | The objective of this project is the development and evaluation of new delivery systems (of anticancer drug using targeting mechanism of magnetic labelled polymeric carriers), for use as carriers of anticancer drugs using targeting mechanism. Biodegradable nanoparticles based on commercially available polymers loaded with selected anticancer drug(s) will be prepared and characterized with the purpose to enhance the amount of drug reaching target site, prolong circulation time and reduce side effects. The objective is to develop and evaluate new magnetic targeted nanoparticles to be localized in a certain region of the body by applying an external magnetic field. Methodologically the project solves the problem of nanoparticle preparation, drug loading of nanoparticles, encapsulation efficiency and anticancer activity of loaded nanoparticles in vitro and in vivo evaluation, construction and evaluation of target efficiency in animal models. New formulation will be evaluated for safety. |
| Duration: | 1.5.2006 – 1.7.2009 |
| Štúdium niektorých fyzikálnych procesov v systémoch obsahujúcich magnetické nanočastice v elektromagnetickom poli | |
| The study of some physical processes in systems containing magnetic nanoparticles in electromagnetic field | |
| Program: | VEGA |
| Project leader: | doc. RNDr. Kopčanský Peter, CSc. |
| Duration: | 1.1.2006 – 31.12.2008 |